HCK

HCK
ساختارهای موجود PDB جستجوی هم‌ساخت‌شناسی: PDBe RCSB فهرست شناسه‌های PDB 1AD5, 1BU1, 1QCF, 2C0I, 2C0O, 2C0T, 2HCK, 2HK5, 2OI3, 2OJ2, 3HCK, 3NHN, 3RBB, 3REA, 3REB, 3VRY, 3VRZ, 3VS0, 3VS1, 3VS2, 3VS3, 3VS4, 3VS5, 3VS6, 3VS7, 4HCK, 4LUD, 4LUE, 4ORZ, 4U5W, 5HCK
معین‌کننده‌ها
نام‌های دیگر	HCK, JTK9, p59Hck, p61Hck, HCK proto-oncogene, Src family tyrosine kinase
شناسه‌های بیرونی	OMIM: 142370 MGI: 96052 HomoloGene: 20489 GeneCards: HCK
موقعیت ژن (موش) کروموزوم کروموزوم ۲ (موش) نوار 2 H1|2 75.41 cM شروع 152,950,388 bp پایان 152,993,361 bp
الگوی گسترش RNA More reference expression data
هستی‌شناسی ژن عملکرد ملکولی • transferase activity • nucleotide binding • protein kinase activity • non-membrane spanning protein tyrosine kinase activity • kinase activity • GO:0001948، GO:0016582 پیوند پروتئینی • signaling receptor binding • ATP binding • protein tyrosine kinase activity • phosphotyrosine residue binding ترکیبات سلولی • سیتوپلاسم • سیتوزول • دستگاه گلژی • cell projection • membrane • focal adhesion • extrinsic component of cytoplasmic side of plasma membrane • transport vesicle • پیوند میان‌یاخته‌ای • ریزرشته • حفره غشایی • کافنده‌تن • اسکلت سلولی • GO:0016023 cytoplasmic vesicle • هسته یاخته • نوکلئوپلاسم • پوسته یاخته فرایند زیستی • دگرگونی یاخته‌ • leukocyte migration involved in immune response • positive regulation of actin filament polymerization • Fc-gamma receptor signaling pathway involved in phagocytosis • فسفرگیری • transmembrane receptor protein tyrosine kinase signaling pathway • cytokine-mediated signaling pathway • interferon-gamma-mediated signaling pathway • immune system process • leukocyte degranulation • negative regulation of apoptotic process • GO:0019049، GO:0030683 mitigation of host defenses by virus • protein phosphorylation • چسبندگی سلولی • respiratory burst after phagocytosis • regulation of DNA-binding transcription factor activity • positive regulation of cell population proliferation • regulation of inflammatory response • regulation of cell shape • regulation of podosome assembly • peptidyl-tyrosine autophosphorylation • بیگانه‌خواری • integrin-mediated signaling pathway • protein autophosphorylation • peptidyl-tyrosine phosphorylation • regulation of phagocytosis • mesoderm development • inflammatory response • innate immune response-activating signal transduction • positive regulation of actin cytoskeleton reorganization • lipopolysaccharide-mediated signaling pathway • اگزوسیتوز • GO:0022415 viral process • دستگاه ایمنی ذاتی منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌ها	انسان	موش
Entrez	3055	15162
آنسامبل	ENSG00000101336	ENSMUSG00000003283
یونی‌پروت	P08631	P08103
RefSeq (mRNA)	NM_001172129، NM_001172130، NM_001172131، NM_001172132، NM_001172133 NM_002110، NM_001172129، NM_001172130، NM_001172131، NM_001172132، NM_001172133	NM_010407 NM_001172117، NM_010407
RefSeq (پروتئین)	NP_001165601، NP_001165602، NP_001165603، NP_001165604، NP_002101 NP_001165600، NP_001165601، NP_001165602، NP_001165603، NP_001165604، NP_002101	NP_034537 NP_001165588، NP_034537
موقعیت (UCSC)	ن/م	Chr : 152.95 – 152.99 Mb
جستجوی PubMed
ویکی‌داده
مشاهده/ویرایش انسان مشاهده/ویرایش موش

تیروزین-پروتئین کیناز HCK (انگلیسی: Tyrosine-protein kinase HCK) یک آنزیم است که در انسان توسط ژن «HCK» کُدگذاری می‌شود.

این پروتئین با گیرنده فاکتور محرک کلونی گرانولوسیت و RASA1 تعامل پروتئین-پروتئین دارد.

منابع

• مشارکت‌کنندگان ویکی‌پدیا. «HCK». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۲۴ اوت ۲۰۱۹.

برای مطالعهٔ بیشتر

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