اینتگرین بتا ۱

ITGB1
ساختارهای موجود
PDB	جستجوی هم‌ساخت‌شناسی: PDBe RCSB
فهرست شناسه‌های PDB
	4WK4, 3G9W, 3T9K, 3VI3, 3VI4, 4DX9, 4WJK, 4WK0, 4WK2
معین‌کننده‌ها
نام‌های دیگر	ITGB1, CD29, FNRB, GPIIA, MDF2, MSK12, VLA-BETA, VLAB, integrin subunit beta 1
شناسه‌های بیرونی	OMIM: 135630 MGI: 96610 HomoloGene: 22999 GeneCards: ITGB1
موقعیت ژن (موش)
کروموزوم	کروموزوم ۸ (موش)
پایان	129,459,681 bp
الگوی گسترش RNA
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• virus receptor activity; • metal ion binding; • integrin binding; • GO:0001948، GO:0016582 پیوند پروتئینی; • laminin binding; • cell adhesion molecule binding; • collagen binding involved in cell-matrix adhesion; • coreceptor activity; • protease binding; • fibronectin binding; • actin binding; • C-X3-C chemokine binding; • protein heterodimerization activity; • GO:0032403 protein-containing complex binding; • cadherin binding; • signaling receptor activity;
ترکیبات سلولی	• سیتوپلاسم; • اندوزوم; • membrane; • melanosome; • ruffle; • integrin alpha8-beta1 complex; • سیناپس; • ruffle membrane; • integrin complex; • perinuclear region of cytoplasm; • cell projection; • dendritic spine; • cell surface; • cleavage furrow; • integrin alpha7-beta1 complex; • extracellular exosome; • پای‌لایه; • integral component of membrane; • recycling endosome; • integrin alpha1-beta1 complex; • صفحات بینابینی; • filopodium; • تماس عصبی-ماهیچه‌ای; • receptor complex; • پوسته یاخته; • integrin alpha11-beta1 complex; • myelin sheath abaxonal region; • synaptic membrane; • integrin alpha10-beta1 complex; • پیوند میان‌یاخته‌ای; • integrin alpha2-beta1 complex; • سارکولما; • external side of plasma membrane; • GO:0016023 cytoplasmic vesicle; • integrin alpha3-beta1 complex; • لیپید رفت; • focal adhesion; • glial cell projection; • Schaffer collateral - CA1 synapse; • glutamatergic synapse; • integral component of synaptic membrane; • GO:0009327 protein-containing complex;
فرایند زیستی	• leukocyte cell-cell adhesion; • cell migration involved in sprouting angiogenesis; • stress fiber assembly; • ورود ویروس; • B cell differentiation; • neuron projection development; • transforming growth factor beta receptor signaling pathway; • regulation of collagen catabolic process; • negative regulation of cell differentiation; • cardiac muscle cell differentiation; • cellular response to low-density lipoprotein particle stimulus; • in utero embryonic development; • cell-substrate adhesion; • GO:0032320، GO:0032321، GO:0032855، GO:0043089، GO:0032854 positive regulation of GTPase activity; • regulation of immune response; • GO:0022415 viral process; • dendrite morphogenesis; • cell fate specification; • گام نخستین رشد; • heterotypic cell-cell adhesion; • extracellular matrix organization; • cell-cell adhesion mediated by integrin; • cellular defense response; • چسبندگی سلولی; • formation of radial glial scaffolds; • axon extension; • leukocyte tethering or rolling; • integrin-mediated signaling pathway; • cell-matrix adhesion; • sarcomere organization; • negative regulation of anoikis; • leukocyte migration; • homophilic cell adhesion via plasma membrane adhesion molecules; • یادگیری بصری; • calcium-independent cell-matrix adhesion; • cardiac muscle tissue development; • negative regulation of Rho protein signal transduction; • receptor internalization; • regulation of cell cycle; • positive regulation of cell population proliferation; • positive regulation of apoptotic process; • mesodermal cell differentiation; • کوچ یاخته; • germ cell migration; • cell adhesion mediated by integrin; • basement membrane organization; • positive regulation of protein localization to plasma membrane; • G1/S transition of mitotic cell cycle; • بیگانه‌خواری; • cytokine-mediated signaling pathway; • cell projection organization; • lamellipodium assembly; • positive regulation of angiogenesis; • modulation of chemical synaptic transmission; • positive regulation of protein kinase B signaling; • positive regulation of signaling receptor activity; • positive regulation of cell migration;
	منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	3688
	16412
	ENSG00000150093
	ENSMUSG00000025809
	P05556
	P09055
	NM_033666، NM_033667، NM_033668، NM_033669، NM_133376 NM_002211، NM_033666، NM_033667، NM_033668، NM_033669، NM_133376
	NM_010578
	NP_391988، NP_596867 NP_002202، NP_391988، NP_596867
	NP_034708
	ویکی‌داده
مشاهده/ویرایش انسان	مشاهده/ویرایش موش

اینتگرین بتا ۱ (انگلیسی: Integrin beta 1) که با نام CD29 هم شناخته می‌شود، یکی از گیرنده‌های سطح سلول است که در انسان توسط ژن «ITGB1» کُدگذاری می‌شود.^[۴] این پروتئین به اینتگرین آلفا ۲ اتصال یافته و ترکیب ساختاری اینتگرین را می‌سازند که به‌عنوان گیرنده کلاژن عمل می‌کند. همچنین به اینتگرین آلفا ۳ متصل شده و در نقشِ گیرنده‌های اینتگرینی برای نترین ۱ و ریلین ظاهر می‌شود.

اهمیت بالینی

در بیماران مبتلا به دیستروفی ماهیچه‌ای کمربند اندام اینتگرین‌های نوع 2C و beta-1D به‌شدت در ماهیچه‌های اسکلتی کاهش یافته‌است که با کاهش اینتگرین آلفا ۷ و فیلامین ۲ مطابقت دارد.^[۵]

در مبتلایان به «پلی‌نورپاتی حساس حرکتی» سطح «اینتگرین آلفا ۷ بی» و «اینتگرین بتا ۱ دی» کاهش شدید داشته تا آنجایی که دیگر قابل ردیابی نیست و این موضوع با کاهش سطح آران‌ای پیام‌رسان مطابقت دارد.^[۶]

فعل و انفعالات

CD29 با پروتئین های زیر تعامل پروتئین-پروتئین دارد:

منابع

↑ ^۱٫۰ ^۱٫۱ ^۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000025809 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Goodfellow PJ, Nevanlinna HA, Gorman P, Sheer D, Lam G, Goodfellow PN (Jan 1989). "Assignment of the gene encoding the beta-subunit of the human fibronectin receptor (beta-FNR) to chromosome 10p11.2". Annals of Human Genetics. 53 (Pt 1): 15–22. doi:10.1111/j.1469-1809.1989.tb01118.x. PMID 2524991.
↑ Anastasi G, Cutroneo G, Trimarchi F, Santoro G, Bruschetta D, Bramanti P, Pisani A, Favaloro A (Dec 2004). "Evaluation of sarcoglycans, vinculin-talin-integrin system and filamin2 in alpha- and gamma-sarcoglycanopathy: an immunohistochemical study". International Journal of Molecular Medicine. 14 (6): 989–99. doi:10.3892/ijmm.14.6.989. PMID 15547664.
↑ Anastasi G, Cutroneo G, Santoro G, Arco A, Rizzo G, Bramanti P, Rinaldi C, Sidoti A, Amato A, Favaloro A (Sep 2008). "Costameric proteins in human skeletal muscle during muscular inactivity". Journal of Anatomy. 213 (3): 284–95. doi:10.1111/j.1469-7580.2008.00921.x. PMC 2732038. PMID 18537849.
↑ Otey CA, Pavalko FM, Burridge K (Aug 1990). "An interaction between alpha-actinin and the beta 1 integrin subunit in vitro". The Journal of Cell Biology. 111 (2): 721–9. doi:10.1083/jcb.111.2.721. PMC 2116186. PMID 2116421.
↑ Otey CA, Vasquez GB, Burridge K, Erickson BW (Oct 1993). "Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain". The Journal of Biological Chemistry. 268 (28): 21193–7. doi:10.1016/S0021-9258(19)36909-1. PMID 7691808.
↑ Lozahic S, Christiansen D, Manié S, Gerlier D, Billard M, Boucheix C, Rubinstein E (Mar 2000). "CD46 (membrane cofactor protein) associates with multiple beta1 integrins and tetraspans". European Journal of Immunology. 30 (3): 900–7. doi:10.1002/1521-4141(200003)30:3<900::AID-IMMU900>3.0.CO;2-X. PMID 10741407.
↑ Radford KJ, Thorne RF, Hersey P (May 1996). "CD63 associates with transmembrane 4 superfamily members, CD9 and CD81, and with beta 1 integrins in human melanoma". Biochemical and Biophysical Research Communications. 222 (1): 13–8. doi:10.1006/bbrc.1996.0690. PMID 8630057.
↑ ^۱۱٫۰ ^۱۱٫۱ Mazzocca A, Carloni V, Sciammetta S, Cordella C, Pantaleo P, Caldini A, Gentilini P, Pinzani M (Sep 2002). "Expression of transmembrane 4 superfamily (TM4SF) proteins and their role in hepatic stellate cell motility and wound healing migration". Journal of Hepatology. 37 (3): 322–30. doi:10.1016/S0168-8278(02)00175-7. PMID 12175627.
↑ Wixler V, Geerts D, Laplantine E, Westhoff D, Smyth N, Aumailley M, Sonnenberg A, Paulsson M (Oct 2000). "The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes". The Journal of Biological Chemistry. 275 (43): 33669–78. doi:10.1074/jbc.M002519200. PMID 10906324.
↑ ^۱۳٫۰ ^۱۳٫۱ van der Flier A, Kuikman I, Kramer D, Geerts D, Kreft M, Takafuta T, Shapiro SS, Sonnenberg A (Jan 2002). "Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits". The Journal of Cell Biology. 156 (2): 361–76. doi:10.1083/jcb.200103037. PMC 2199218. PMID 11807098.
↑ Loo DT, Kanner SB, Aruffo A (Sep 1998). "Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction". The Journal of Biological Chemistry. 273 (36): 23304–12. doi:10.1074/jbc.273.36.23304. PMID 9722563.
↑ Serru V, Le Naour F, Billard M, Azorsa DO, Lanza F, Boucheix C, Rubinstein E (May 1999). "Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions". The Biochemical Journal. 340 (Pt 1): 103–11. doi:10.1042/0264-6021:3400103. PMC 1220227. PMID 10229664.
↑ ^۱۶٫۰ ^۱۶٫۱ Lee HS, Millward-Sadler SJ, Wright MO, Nuki G, Al-Jamal R, Salter DM (Nov 2002). "Activation of Integrin-RACK1/PKCalpha signalling in human articular chondrocyte mechanotransduction". Osteoarthritis and Cartilage. 10 (11): 890–7. doi:10.1053/joca.2002.0842. PMID 12435334.
↑ Liliental J, Chang DD (Jan 1998). "Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit". The Journal of Biological Chemistry. 273 (4): 2379–83. doi:10.1074/jbc.273.4.2379. PMID 9442085.
↑ Chang DD, Wong C, Smith H, Liu J (Sep 1997). "ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin". The Journal of Cell Biology. 138 (5): 1149–57. doi:10.1083/jcb.138.5.1149. PMC 2136751. PMID 9281591.
↑ Chang DD, Hoang BQ, Liu J, Springer TA (Mar 2002). "Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin". The Journal of Biological Chemistry. 277 (10): 8140–5. doi:10.1074/jbc.M109031200. PMID 11741908.
↑ Hadari YR, Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (Jul 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". Journal of Cell Science. 113 (13): 2385–97. doi:10.1242/jcs.113.13.2385. PMID 10852818.
↑ Poinat P, De Arcangelis A, Sookhareea S, Zhu X, Hedgecock EM, Labouesse M, Georges-Labouesse E (Apr 2002). "A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans". Current Biology. 12 (8): 622–31. doi:10.1016/S0960-9822(02)00764-9. PMID 11967148. S2CID 9977605.
↑ Fournier HN, Dupé-Manet S, Bouvard D, Lacombe ML, Marie C, Block MR, Albiges-Rizo C (Jun 2002). "Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement". The Journal of Biological Chemistry. 277 (23): 20895–902. doi:10.1074/jbc.M200200200. PMID 11919189.
↑ Parsons M, Keppler MD, Kline A, Messent A, Humphries MJ, Gilchrist R, Hart IR, Quittau-Prevostel C, Hughes WE, Parker PJ, Ng T (Aug 2002). "Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis". Molecular and Cellular Biology. 22 (16): 5897–911. doi:10.1128/MCB.22.16.5897-5911.2002. PMC 133968. PMID 12138200.
↑ Tapley P, Horwitz A, Buck C, Duggan K, Rohrschneider L (Mar 1989). "Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts". Oncogene. 4 (3): 325–33. PMID 2468126.
↑ Horwitz A, Duggan K, Buck C, Beckerle MC, Burridge K (1986). "Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage". Nature. 320 (6062): 531–3. Bibcode:1986Natur.320..531H. doi:10.1038/320531a0. PMID 2938015. S2CID 4356748.
↑ Tachibana I, Bodorova J, Berditchevski F, Zutter MM, Hemler ME (Nov 1997). "NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins". The Journal of Biological Chemistry. 272 (46): 29181–9. doi:10.1074/jbc.272.46.29181. PMID 9360996.
↑ Han DC, Rodriguez LG, Guan JL (Jan 2001). "Identification of a novel interaction between integrin beta1 and 14-3-3beta". Oncogene. 20 (3): 346–57. doi:10.1038/sj.onc.1204068. PMID 11313964.

مشارکت‌کنندگان ویکی‌پدیا. «Integrin beta 1». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۲۳ اوت ۲۰۱۹.

برای مطالعهٔ بیشتر

Evans JP (Jul 2001). "Fertilin beta and other ADAMs as integrin ligands: insights into cell adhesion and fertilization". BioEssays. 23 (7): 628–39. doi:10.1002/bies.1088. PMID 11462216.
Armulik A (Jan 2002). "Splice variants of human beta 1 integrins: origin, biosynthesis and functions". Frontiers in Bioscience. 7: d219-27. doi:10.2741/armulik. PMID 11779688.
Brakebusch C, Fässler R (Sep 2005). "beta 1 integrin function in vivo: adhesion, migration and more". Cancer Metastasis Reviews. 24 (3): 403–11. doi:10.1007/s10555-005-5132-5. PMID 16258728.

پیوند به بیرون

CD29 Antigen در سرعنوان‌های موضوعی پزشکی (MeSH) در کتابخانهٔ ملی پزشکی ایالات متحدهٔ آمریکا
مکان ژنوم ITGB1 انسانی و صفحهٔ جزئیات ژنی ITGB1 در سامانه جستجوی بانک ژنی دانشگاه کالیفرنیا، سانتا کروز.

[refGRCm38Ensembl-1] ۱٫۰ ^۱٫۱ ^۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000025809 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid_2524991-4] Goodfellow PJ, Nevanlinna HA, Gorman P, Sheer D, Lam G, Goodfellow PN (Jan 1989). "Assignment of the gene encoding the beta-subunit of the human fibronectin receptor (beta-FNR) to chromosome 10p11.2". Annals of Human Genetics. 53 (Pt 1): 15–22. doi:10.1111/j.1469-1809.1989.tb01118.x. PMID 2524991.

[5] Anastasi G, Cutroneo G, Trimarchi F, Santoro G, Bruschetta D, Bramanti P, Pisani A, Favaloro A (Dec 2004). "Evaluation of sarcoglycans, vinculin-talin-integrin system and filamin2 in alpha- and gamma-sarcoglycanopathy: an immunohistochemical study". International Journal of Molecular Medicine. 14 (6): 989–99. doi:10.3892/ijmm.14.6.989. PMID 15547664.

[6] Anastasi G, Cutroneo G, Santoro G, Arco A, Rizzo G, Bramanti P, Rinaldi C, Sidoti A, Amato A, Favaloro A (Sep 2008). "Costameric proteins in human skeletal muscle during muscular inactivity". Journal of Anatomy. 213 (3): 284–95. doi:10.1111/j.1469-7580.2008.00921.x. PMC 2732038. PMID 18537849.

[7] Otey CA, Pavalko FM, Burridge K (Aug 1990). "An interaction between alpha-actinin and the beta 1 integrin subunit in vitro". The Journal of Cell Biology. 111 (2): 721–9. doi:10.1083/jcb.111.2.721. PMC 2116186. PMID 2116421.

[8] Otey CA, Vasquez GB, Burridge K, Erickson BW (Oct 1993). "Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain". The Journal of Biological Chemistry. 268 (28): 21193–7. doi:10.1016/S0021-9258(19)36909-1. PMID 7691808.

[pmid10741407-9] Lozahic S, Christiansen D, Manié S, Gerlier D, Billard M, Boucheix C, Rubinstein E (Mar 2000). "CD46 (membrane cofactor protein) associates with multiple beta1 integrins and tetraspans". European Journal of Immunology. 30 (3): 900–7. doi:10.1002/1521-4141(200003)30:3<900::AID-IMMU900>3.0.CO;2-X. PMID 10741407.

[pmid8630057-10] Radford KJ, Thorne RF, Hersey P (May 1996). "CD63 associates with transmembrane 4 superfamily members, CD9 and CD81, and with beta 1 integrins in human melanoma". Biochemical and Biophysical Research Communications. 222 (1): 13–8. doi:10.1006/bbrc.1996.0690. PMID 8630057.

[pmid12175627-11] ۱۱٫۰ ^۱۱٫۱ Mazzocca A, Carloni V, Sciammetta S, Cordella C, Pantaleo P, Caldini A, Gentilini P, Pinzani M (Sep 2002). "Expression of transmembrane 4 superfamily (TM4SF) proteins and their role in hepatic stellate cell motility and wound healing migration". Journal of Hepatology. 37 (3): 322–30. doi:10.1016/S0168-8278(02)00175-7. PMID 12175627.

[pmid10906324-12] Wixler V, Geerts D, Laplantine E, Westhoff D, Smyth N, Aumailley M, Sonnenberg A, Paulsson M (Oct 2000). "The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes". The Journal of Biological Chemistry. 275 (43): 33669–78. doi:10.1074/jbc.M002519200. PMID 10906324.

[pmid11807098-13] ۱۳٫۰ ^۱۳٫۱ van der Flier A, Kuikman I, Kramer D, Geerts D, Kreft M, Takafuta T, Shapiro SS, Sonnenberg A (Jan 2002). "Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits". The Journal of Cell Biology. 156 (2): 361–76. doi:10.1083/jcb.200103037. PMC 2199218. PMID 11807098.

[pmid9722563-14] Loo DT, Kanner SB, Aruffo A (Sep 1998). "Filamin binds to the cytoplasmic domain of the beta1-integrin. Identification of amino acids responsible for this interaction". The Journal of Biological Chemistry. 273 (36): 23304–12. doi:10.1074/jbc.273.36.23304. PMID 9722563.

[pmid10229664-15] Serru V, Le Naour F, Billard M, Azorsa DO, Lanza F, Boucheix C, Rubinstein E (May 1999). "Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions". The Biochemical Journal. 340 (Pt 1): 103–11. doi:10.1042/0264-6021:3400103. PMC 1220227. PMID 10229664.

[pmid12435334-16] ۱۶٫۰ ^۱۶٫۱ Lee HS, Millward-Sadler SJ, Wright MO, Nuki G, Al-Jamal R, Salter DM (Nov 2002). "Activation of Integrin-RACK1/PKCalpha signalling in human articular chondrocyte mechanotransduction". Osteoarthritis and Cartilage. 10 (11): 890–7. doi:10.1053/joca.2002.0842. PMID 12435334.

[pmid9442085-17] Liliental J, Chang DD (Jan 1998). "Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit". The Journal of Biological Chemistry. 273 (4): 2379–83. doi:10.1074/jbc.273.4.2379. PMID 9442085.

[pmid9281591-18] Chang DD, Wong C, Smith H, Liu J (Sep 1997). "ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin". The Journal of Cell Biology. 138 (5): 1149–57. doi:10.1083/jcb.138.5.1149. PMC 2136751. PMID 9281591.

[pmid11741908-19] Chang DD, Hoang BQ, Liu J, Springer TA (Mar 2002). "Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin". The Journal of Biological Chemistry. 277 (10): 8140–5. doi:10.1074/jbc.M109031200. PMID 11741908.

[pmid10852818-20] Hadari YR, Arbel-Goren R, Levy Y, Amsterdam A, Alon R, Zakut R, Zick Y (Jul 2000). "Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis". Journal of Cell Science. 113 (13): 2385–97. doi:10.1242/jcs.113.13.2385. PMID 10852818.

[pmid11967148-21] Poinat P, De Arcangelis A, Sookhareea S, Zhu X, Hedgecock EM, Labouesse M, Georges-Labouesse E (Apr 2002). "A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans". Current Biology. 12 (8): 622–31. doi:10.1016/S0960-9822(02)00764-9. PMID 11967148. S2CID 9977605.

[pmid11919189-22] Fournier HN, Dupé-Manet S, Bouvard D, Lacombe ML, Marie C, Block MR, Albiges-Rizo C (Jun 2002). "Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement". The Journal of Biological Chemistry. 277 (23): 20895–902. doi:10.1074/jbc.M200200200. PMID 11919189.

[pmid12138200-23] Parsons M, Keppler MD, Kline A, Messent A, Humphries MJ, Gilchrist R, Hart IR, Quittau-Prevostel C, Hughes WE, Parker PJ, Ng T (Aug 2002). "Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis". Molecular and Cellular Biology. 22 (16): 5897–911. doi:10.1128/MCB.22.16.5897-5911.2002. PMC 133968. PMID 12138200.

[24] Tapley P, Horwitz A, Buck C, Duggan K, Rohrschneider L (Mar 1989). "Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts". Oncogene. 4 (3): 325–33. PMID 2468126.

[25] Horwitz A, Duggan K, Buck C, Beckerle MC, Burridge K (1986). "Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage". Nature. 320 (6062): 531–3. Bibcode:1986Natur.320..531H. doi:10.1038/320531a0. PMID 2938015. S2CID 4356748.

[pmid9360996-26] Tachibana I, Bodorova J, Berditchevski F, Zutter MM, Hemler ME (Nov 1997). "NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins". The Journal of Biological Chemistry. 272 (46): 29181–9. doi:10.1074/jbc.272.46.29181. PMID 9360996.

[pmid11313964-27] Han DC, Rodriguez LG, Guan JL (Jan 2001). "Identification of a novel interaction between integrin beta1 and 14-3-3beta". Oncogene. 20 (3): 346–57. doi:10.1038/sj.onc.1204068. PMID 11313964.

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