GNAI1

GNAI1
ساختارهای موجود PDB جستجوی هم‌ساخت‌شناسی: PDBe RCSB فهرست شناسه‌های PDB 1KJY, 1Y3A, 2G83, 2GTP, 2IK8, 2OM2, 2XNS, 3ONW, 3QE0, 3QI2, 3UMR, 3UMS, 4G5Q, 5JS7, 5JS8
معین‌کننده‌ها
نام‌های دیگر	GNAI1, Gi, G protein subunit alpha i1, HG1B, NEDHISB
شناسه‌های بیرونی	OMIM: 139310 MGI: 95771 HomoloGene: 74417 GeneCards: GNAI1
موقعیت ژن (موش) کروموزوم کروموزوم ۵ (موش) نوار 5 A3|5 8.16 cM شروع 18,470,133 bp پایان 18,565,353 bp
الگوی گسترش RNA More reference expression data
هستی‌شناسی ژن عملکرد ملکولی • GTPase activating protein binding • nucleotide binding • G-protein beta/gamma-subunit complex binding • GDP binding • G protein-coupled serotonin receptor binding • signal transducer activity • metal ion binding • GO:0001948، GO:0016582 پیوند پروتئینی • guanyl nucleotide binding • G protein-coupled receptor binding • GTP binding • magnesium ion binding • GO:0006184 GTPase activity ترکیبات سلولی • سیتوپلاسم • میان‌تن • membrane • پوسته یاخته • intracellular anatomical structure • microtubule organizing center • lysosomal membrane • midbody • heterotrimeric G-protein complex • لیپید رفت • extracellular exosome • اسکلت سلولی • هسته یاخته • هستک • cell cortex region • cell cortex • GO:0009327 protein-containing complex فرایند زیستی • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • response to peptide hormone • negative regulation of synaptic transmission • تقسیم یاخته • چرخه یاخته‌ای • GO:0072468 ورارسانی پیام • regulation of cAMP-mediated signaling • cellular response to forskolin • تاشدگی پروتئین • regulation of mitotic spindle organization • positive regulation of protein localization to cell cortex • GO:0015915 transport • G protein-coupled receptor signaling pathway منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌ها	انسان	موش
Entrez	2770	14677
آنسامبل	ENSG00000127955	ENSMUSG00000057614
یونی‌پروت	P63096	B2RSH2
RefSeq (mRNA)	NM_001256414 NM_002069، NM_001256414	NM_010305
RefSeq (پروتئین)	NP_002060 NP_001243343، NP_002060	NP_034435
موقعیت (UCSC)	ن/م	Chr : 18.47 – 18.57 Mb
جستجوی PubMed
ویکی‌داده
مشاهده/ویرایش انسان مشاهده/ویرایش موش

پروتئین جی متصل‌شونده به نوکلئوتید گوانین، زیرواحد آلفا-۱ (انگلیسی: Guanine nucleotide-binding protein G(i), alpha-1 subunit) یک پروتئین است که در انسان توسط ژن «GNAI1» کُدگذاری می‌شود.

منابع

• مشارکت‌کنندگان ویکی‌پدیا. «GNAI1». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۳۰ دسامبر ۲۰۱۸.

برای مطالعهٔ بیشتر

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