FZD5

FZD5
معین‌کننده‌ها
نام‌های دیگر	FZD5, C2orf31, HFZ5, frizzled class receptor 5
شناسه‌های بیرونی	OMIM: 601723 MGI: 108571 HomoloGene: 2590 GeneCards: FZD5
موقعیت ژن (موش) کروموزوم کروموزوم ۱ (موش) نوار 1 C2|1 32.74 cM شروع 64,769,717 bp پایان 64,776,910 bp
الگوی گسترش RNA More reference expression data
هستی‌شناسی ژن عملکرد ملکولی • amyloid-beta binding • signal transducer activity • Wnt-protein binding • GO:0001948، GO:0016582 پیوند پروتئینی • protein kinase binding • ubiquitin protein ligase binding • transmembrane signaling receptor activity • Wnt-activated receptor activity • G protein-coupled receptor activity ترکیبات سلولی • clathrin-coated endocytic vesicle membrane • دستگاه گلژی • early endosome membrane • membrane • bicellular tight junction • Golgi membrane • پوسته یاخته • cell surface • early endosome • perinuclear region of cytoplasm • integral component of membrane فرایند زیستی • G protein-coupled receptor signaling pathway • T cell differentiation in thymus • chorionic trophoblast cell differentiation • positive regulation of protein targeting to mitochondrion • positive regulation of JUN kinase activity • apoptotic process involved in morphogenesis • regulation of chorionic trophoblast cell proliferation • regulation of bicellular tight junction assembly • regulation of canonical Wnt signaling pathway • cellular response to molecule of bacterial origin • positive regulation of interferon-gamma production • embryonic axis specification • labyrinthine layer blood vessel development • cell maturation • Wnt signaling pathway • embryonic camera-type eye development • multicellular organism development • cell surface receptor signaling pathway • vasculature development • regulation of autophagy of mitochondrion • branching involved in labyrinthine layer morphogenesis • embryonic camera-type eye morphogenesis • post-embryonic camera-type eye development • positive regulation of T cell cytokine production • رگ‌زایی • neuron differentiation • Wnt signaling pathway involved in dorsal/ventral axis specification • canonical Wnt signaling pathway • سیناپتوژنز • syncytiotrophoblast cell differentiation involved in labyrinthine layer development • anterior/posterior axis specification, embryo • Spemann organizer formation • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 positive regulation of transcription by RNA polymerase II • negative regulation of cell population proliferation • GO:0072468 ورارسانی پیام • Wnt signaling pathway, calcium modulating pathway • Wnt signaling pathway, planar cell polarity pathway • beta-catenin destruction complex disassembly منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌ها	انسان	موش
Entrez	7855	14367
آنسامبل	ENSG00000163251	ENSMUSG00000045005
یونی‌پروت	Q13467	Q9EQD0
RefSeq (mRNA)	NM_003468 NM_030804، NM_003468	NM_001042659، NM_022721 NM_001033193، NM_001042659، NM_022721
RefSeq (پروتئین)	XP_024308898 NP_003459، XP_024308898	NP_073558 NP_001036124، NP_073558
موقعیت (UCSC)	ن/م	Chr : 64.77 – 64.78 Mb
جستجوی PubMed
ویکی‌داده
مشاهده/ویرایش انسان مشاهده/ویرایش موش

فریزلد ۵ (انگلیسی: Frizzled-5) یک پروتئین است که در انسان توسط ژن «FZD5» کدگذاری می‌شود.

اعضای خانوادهٔ ژن‌های فریزلد، یک گیرنده جفت‌شونده با پروتئین جی با هفت دومین پروتئینی تراغشایی را کد می‌کنند که همگی پروتئین‌های مسیر سیگنالینگ Wnt هستند.

منابع

• مشارکت‌کنندگان ویکی‌پدیا. «FZD5». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۲۸ دسامبر ۲۰۱۸.

برای مطالعهٔ بیشتر

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