TTLL1

TTLL1
معین‌کننده‌ها
نام‌های دیگر	TTLL1, C22orf7, HS323M22B, tubulin tyrosine ligase like 1, TTL family tubulin polyglutamylase complex subunit L1, TPGS3
شناسه‌های بیرونی	OMIM: 608955 MGI: 2443047 HomoloGene: 8174 GeneCards: TTLL1
موقعیت ژن (موش)
کروموزوم	کروموزوم ۱۵ (موش)
پایان	83,395,094 bp
الگوی گسترش RNA
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• nucleotide binding; • ligase activity; • ATP binding; • tubulin-glutamic acid ligase activity;
ترکیبات سلولی	• سیتوپلاسم; • ریزلوله; • اسکلت سلولی; • extracellular region;
فرایند زیستی	• epithelial cilium movement involved in extracellular fluid movement; • protein polyglutamylation; • axoneme assembly; • sperm axoneme assembly;
	منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	25809
	319953
	ENSG00000100271
	ENSMUSG00000022442
	O95922
	Q91V51
	NM_012263، NR_027779 NM_001008572، NM_012263، NR_027779
	XM_006521078، NM_001357953، XM_030248606 NM_178869، XM_006521078، NM_001357953، XM_030248606
	XP_006724288، XP_011528410، XP_011528412، XP_016884240، XP_016884241، XP_016884242 NP_036395، XP_006724288، XP_011528410، XP_011528412، XP_016884240، XP_016884241، XP_016884242
	XP_006521141، NP_001344882، XP_030104466 NP_849200، XP_006521141، NP_001344882، XP_030104466
	ویکی‌داده
مشاهده/ویرایش انسان	مشاهده/ویرایش موش

توبولین پلی‌گلوتامیلاز احتمالی TTLL1 آنزیمی است که در انسان توسط ژن TTLL1 کدگذاری می‌شود.^[۴]^[۵]^[۶]

منابع[ویرایش]

↑ ^۱٫۰ ^۱٫۱ ^۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000022442 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
↑ Trichet V, Ruault M, Roizes G, De Sario A (Dec 2000). "Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1". Gene. 257 (1): 109–17. doi:10.1016/S0378-1119(00)00383-8. PMID 11054573.
↑ "Entrez Gene: TTLL1 tubulin tyrosine ligase-like family, member 1".

جهت مطالعه[ویرایش]

Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Janke C, Rogowski K, Wloga D, et al. (2005). "Tubulin polyglutamylase enzymes are members of the TTL domain protein family". Science. 308 (5729): 1758–62. doi:10.1126/science.1113010. PMID 15890843. S2CID 25798588.

[refGRCm38Ensembl-1] ۱٫۰ ^۱٫۱ ^۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000022442 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid_10591208-4] Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.

[pmid_11054573-5] Trichet V, Ruault M, Roizes G, De Sario A (Dec 2000). "Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1". Gene. 257 (1): 109–17. doi:10.1016/S0378-1119(00)00383-8. PMID 11054573.

[entrez-6] "Entrez Gene: TTLL1 tubulin tyrosine ligase-like family, member 1".

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