الگو:PBB/3156

3-hydroxy-3-methylglutaryl-CoA reductase
بانک داده پروتئین rendering based on 1dq8.
ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 1DQ8, 1DQ9, 1DQA, 1HW8, 1HW9, 1HWI, 1HWJ, 1HWK, 1HWL, 2Q1L, 2Q6B, 2Q6C, 2R4F, 3BGL, 3CCT, 3CCW, 3CCZ, 3CD0, 3CD5, 3CD7, 3CDA, 3CDB
شاخص‌ها
نماد ژن	HMGCR; LDLCQ3
شناسه‌های بیرونی	OMIM: 142910 MGI: 96159 HomoloGene: 30994 ChEMBL: 402 GeneCards: HMGCR Gene
EC number	1.1.1.34
هستی‌شناسی ژن Molecular function • hydroxymethylglutaryl-CoA reductase (NADPH) activity • protein binding • hydroxymethylglutaryl-CoA reductase activity • protein homodimerization activity • coenzyme binding • protein phosphatase 2A binding • NADPH binding Cellular component • intracellular • peroxisomal membrane • endoplasmic reticulum • endoplasmic reticulum membrane • integral component of membrane Biological process • cholesterol biosynthetic process • ubiquinone metabolic process • aging • response to nutrient • isoprenoid biosynthetic process • visual learning • negative regulation of striated muscle cell apoptotic process • positive regulation of cardiac muscle cell apoptotic process • coenzyme A metabolic process • positive regulation of stress-activated MAPK cascade • negative regulation of MAP kinase activity • cellular lipid metabolic process • small molecule metabolic process • myoblast differentiation • response to ethanol • negative regulation of vasodilation • positive regulation of skeletal muscle tissue development • positive regulation of smooth muscle cell proliferation • protein tetramerization • oxidation-reduction process • negative regulation of wound healing • negative regulation of insulin secretion involved in cellular response to glucose stimulus • positive regulation of ERK1 and ERK2 cascade Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	3156	15357
آنسامبل	ENSG00000113161	ENSMUSG00000021670
UniProt	P04035	Q01237
RefSeq (mRNA)	NM_000859	NM_008255
RefSeq (protein)	NP_000850	NP_032281
موقعیت (UCSC)	Chr 5: 75.34 – 75.36 Mb	Chr 13: 96.65 – 96.67 Mb
جستجوی پاب‌مد	[۱]	[۲]