الگو:PBB/10392

Nucleotide-binding oligomerization domain containing 1
PDB rendering based on 2b1w.
ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 2B1W, 2DBD, 2NSN, 2NZ7, 4E9M
شاخص‌ها
نماد ژن	NOD1; CARD4; CLR7.1; NLRC1
شناسه‌های بیرونی	OMIM: 605980 MGI: 1341839 HomoloGene: 4440 ChEMBL: 1293222 GeneCards: NOD1 Gene
هستی‌شناسی ژن Molecular function • protein binding • ATP binding • cysteine-type endopeptidase activator activity involved in apoptotic process • identical protein binding • protein homodimerization activity • peptidoglycan binding • CARD domain binding Cellular component • cytoplasm • cytosol • basolateral plasma membrane Biological process • activation of MAPK activity • toll-like receptor signaling pathway • positive regulation of dendritic cell antigen processing and presentation • MyD88-dependent toll-like receptor signaling pathway • MyD88-independent toll-like receptor signaling pathway • apoptotic process • induction of apoptosis • activation of cysteine-type endopeptidase activity involved in apoptotic process • defense response • inflammatory response • signal transduction • JNK cascade • Toll signaling pathway • detection of biotic stimulus • detection of bacterium • positive regulation of interleukin-6 production • positive regulation of tumor necrosis factor production • toll-like receptor 1 signaling pathway • toll-like receptor 2 signaling pathway • toll-like receptor 3 signaling pathway • toll-like receptor 4 signaling pathway • intracellular signal transduction • TRIF-dependent toll-like receptor signaling pathway • nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway • interleukin-8 biosynthetic process • defense response to bacterium • positive regulation of I-kappaB kinase/NF-kappaB cascade • innate immune response • positive regulation of JNK cascade • defense response to Gram-positive bacterium • positive regulation of NF-kappaB transcription factor activity • protein oligomerization • stress-activated MAPK cascade • positive regulation of ERK1 and ERK2 cascade • nucleotide-binding oligomerization domain containing signaling pathway Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	10392	107607
آنسامبل	ENSG00000106100	ENSMUSG00000038058
UniProt	Q9Y239	Q8BHB0
RefSeq (mRNA)	NM_006092.2	NM_001171007.1
RefSeq (protein)	NP_006083.1	NP_001164478.1
موقعیت (UCSC)	Chr 7: 30.46 – 30.52 Mb	Chr 6: 54.92 – 54.97 Mb
جستجوی پاب‌مد	[۱]	[۲]