الگو:PBB/1027

Cyclin-dependent kinase inhibitor 1B (p27, Kip1)
PDB rendering based on 1jsu.
ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 1H27, 1JSU, 2AST
شاخص‌ها
نماد ژن	CDKN1B; CDKN4; KIP1; MEN1B; MEN4; P27KIP1
شناسه‌های بیرونی	OMIM: 600778 MGI: 104565 HomoloGene: 2999 GeneCards: CDKN1B Gene
هستی‌شناسی ژن Molecular function • cyclin-dependent protein kinase inhibitor activity • transforming growth factor beta receptor, cytoplasmic mediator activity • protein binding • cysteine-type endopeptidase activator activity involved in apoptotic process • protein phosphatase binding Cellular component • nucleus • nucleoplasm • cytoplasm • endosome • cytosol Biological process • cell cycle checkpoint • regulation of cyclin-dependent protein kinase activity • G1 phase of mitotic cell cycle • G1/S transition of mitotic cell cycle • S phase of mitotic cell cycle • mitotic cell cycle • potassium ion transport • induction of apoptosis • activation of cysteine-type endopeptidase activity involved in apoptotic process • DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest • cell cycle arrest • epidermal growth factor receptor signaling pathway • sensory perception of sound • positive regulation of cell proliferation • negative regulation of cell proliferation • fibroblast growth factor receptor signaling pathway • positive regulation of cell death • negative regulation of cell growth • positive regulation of microtubule polymerization • negative regulation of kinase activity • negative regulation of phosphorylation • negative regulation of apoptotic process • positive regulation of protein catabolic process • negative regulation of cyclin-dependent protein kinase activity • negative regulation of transcription, DNA-dependent • negative regulation of mitotic cell cycle • nerve growth factor receptor signaling pathway • phosphatidylinositol-mediated signaling • autophagic cell death • inner ear development • negative regulation of cellular component movement • negative regulation of epithelial cell proliferation involved in prostate gland development • cellular response to antibiotic • cellular response to lithium ion • cellular response to organic cyclic compound • mitotic cell cycle arrest Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	1027	12576
آنسامبل	ENSG00000111276	ENSMUSG00000003031
UniProt	P46527	P46414
RefSeq (mRNA)	NM_004064.3	NM_009875.4
RefSeq (protein)	NP_004055.1	NP_034005.2
موقعیت (UCSC)	Chr 12: 12.87 – 12.88 Mb	Chr 6: 134.92 – 134.93 Mb
جستجوی پاب‌مد	[۱]	[۲]