الگو:PBB/10210

Topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
شاخص‌ها
نماد ژن	TOPORS; LUN; P53BP3; RP31; TP53BPL
شناسه‌های بیرونی	OMIM: 609507 MGI: 2146189 HomoloGene: 4237 GeneCards: TOPORS Gene
هستی‌شناسی ژن Molecular function • DNA binding • antigen binding • ubiquitin-protein ligase activity • protein binding • zinc ion binding • SUMO ligase activity • DNA topoisomerase binding Cellular component • spindle pole • gamma-tubulin complex • nucleus • centriole • cytoplasmic dynein complex • PML body • nuclear speck • midbody • photoreceptor connecting cilium • cilium basal body Biological process • transcription, DNA-dependent • ubiquitin-dependent protein catabolic process • protein monoubiquitination • apoptotic process • response to DNA damage stimulus • intrinsic apoptotic signaling pathway in response to DNA damage response • retina layer formation • protein sumoylation • protein localization to nucleus • photoreceptor cell outer segment organization • regulation of cell proliferation • negative regulation of apoptotic process • proteasomal ubiquitin-dependent protein catabolic process • positive regulation of transcription, DNA-dependent • retinal rod cell development • retinal cone cell development • positive regulation of ubiquitin-protein ligase activity • maintenance of protein location in nucleus • protein K48-linked ubiquitination Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	10210	106021
آنسامبل	ENSG00000197579	ENSMUSG00000036822
UniProt	Q9NS56	Q80Z37
RefSeq (mRNA)	NM_001195622.1	NM_134097.3
RefSeq (protein)	NP_001182551.1	NP_598858.2
موقعیت (UCSC)	Chr 9: 32.54 – 32.55 Mb	Chr 4: 40.26 – 40.27 Mb
جستجوی پاب‌مد	[۱]	[۲]