الگو:PBB/102

ADAM metallopeptidase domain 10
PDB rendering based on 2ao7.
ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 1M1I
شاخص‌ها
نماد ژن	ADAM10; AD10; CD156c; HsT18717; MADM; kuz
شناسه‌های بیرونی	OMIM: 602192 MGI: 109548 HomoloGene: 865 ChEMBL: 5028 GeneCards: ADAM10 Gene
EC number	3.4.24.81
هستی‌شناسی ژن Molecular function • endopeptidase activity • metalloendopeptidase activity • receptor binding • integrin binding • protein binding • metallopeptidase activity • zinc ion binding • SH3 domain binding • protein kinase binding • protein homodimerization activity Cellular component • nucleus • cytoplasm • Golgi apparatus • Golgi-associated vesicle • plasma membrane • cell surface • endomembrane system • postsynaptic density • integral to membrane Biological process • in utero embryonic development • protein phosphorylation • membrane protein ectodomain proteolysis • negative regulation of cell adhesion • epidermal growth factor receptor signaling pathway • Notch signaling pathway • Notch receptor processing • integrin-mediated signaling pathway • cell-cell signaling • positive regulation of cell proliferation • positive regulation of T cell chemotaxis • positive regulation of cell growth • positive regulation of cell migration • response to tumor necrosis factor • monocyte activation • PMA-inducible membrane protein ectodomain proteolysis • constitutive protein ectodomain proteolysis Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	102	11487
آنسامبل	ENSG00000137845	ENSMUSG00000054693
UniProt	O14672	O35598
RefSeq (mRNA)	NM_001110.2	NM_007399.3
RefSeq (protein)	NP_001101.1	NP_031425.2
موقعیت (UCSC)	Chr 15: 58.89 – 59.04 Mb	Chr 9: 70.68 – 70.78 Mb
جستجوی پاب‌مد	[۱]	[۲]