الگو:PBB/10203

Calcitonin receptor-like
Calcitonin receptor-like
	Crystallographic structure of the ectodomain complex of the CGRP type 1 receptor and RAMP1.
ساختارهای موجود
بانک داده پروتئین	Ortholog search: PDBe, RCSB
فهرست کدهای شناسه PDB
	3AQF, 3N7P, 3N7R, 3N7S
شاخص‌ها
نماد ژن	CALCRL; CGRPR; CRLR
شناسه‌های بیرونی	OMIM: 114190 MGI: 1926944 HomoloGene: 21179 IUPHAR: calcitonin receptor-like ChEMBL: 3798 GeneCards: CALCRL Gene
هستی‌شناسی ژن
Molecular function	• adrenomedullin receptor activity; • calcitonin gene-related polypeptide receptor activity; • G-protein coupled receptor activity; • calcitonin receptor activity; • protein binding; • protein transporter activity;
Cellular component	• lysosome; • endosome; • endoplasmic reticulum; • plasma membrane; • integral to plasma membrane;
Biological process	• angiogenesis; • cAMP biosynthetic process; • calcium ion transport; • regulation of muscle contraction; • G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; • adenylate cyclase-activating G-protein coupled receptor signaling pathway; • heart development; • protein transport; • positive regulation of cAMP biosynthetic process; • receptor internalization; • positive regulation of smooth muscle cell proliferation; • negative regulation of inflammatory response; • cellular response to sucrose stimulus;
	Sources: Amigo / QuickGO
الگوی بیان RNA
	دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان
آنتره	10203
آنسامبل	ENSG00000064989
UniProt	Q16602
RefSeq (mRNA)	NM_005795.4
RefSeq (protein)	NP_005786.1
موقعیت (UCSC)	Chr 2:; 188.21 – 188.31 Mb
جستجوی پاب‌مد	[۱]
	ن; ب; و;

منابع

↑ پی‌دی‌بی 3N7S; ter Haar E, Koth CM, Abdul-Manan N, Swenson L, Coll JT, Lippke JA, Lepre CA, Garcia-Guzman M, Moore JM (2010). "Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism". Structure. 18 (9): 1083–93. doi:10.1016/j.str.2010.05.014. PMID 20826335. {{cite journal}}: Unknown parameter |month= ignored (help)نگهداری یادکرد:نام‌های متعدد:فهرست نویسندگان (link)

[pmid20826335-1] پی‌دی‌بی 3N7S; ter Haar E, Koth CM, Abdul-Manan N, Swenson L, Coll JT, Lippke JA, Lepre CA, Garcia-Guzman M, Moore JM (2010). "Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism". Structure. 18 (9): 1083–93. doi:10.1016/j.str.2010.05.014. PMID 20826335. {{cite journal}}: Unknown parameter |month= ignored (help)نگهداری یادکرد:نام‌های متعدد:فهرست نویسندگان (link)

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