English: "(A) Schematic depiction describing the sEmbryo culture protocol steps from day 0 to day 8 (upper panel). Representative images of 24-well Aggrewell plates used for sEmbryo static culture (day 0 – day 3) and sEmbryos in non-adherent 6 well plate placed on orbital shaker inside a regular tissue culture incubator at day 4.

(B) Images of sEmbryos transferred to in house generated electronically controlled rolling culture platform and glass bottles on day 5. (C) Representative images of sEmbryos at day 6 in the electronically controlled ex utero roller culture system.

(D) Day 5–8 representative images showing the growth of sEmbryo inside glass bottles in the ex utero roller culture system used herein, in EUCM conditions."