الگو:PBB/101

ADAM metallopeptidase domain 8
ساختارهای موجود بانک داده پروتئین Ortholog search: PDBe, RCSB فهرست کدهای شناسه PDB 4DD8
شاخص‌ها
نماد ژن	ADAM8; CD156; MS2
شناسه‌های بیرونی	OMIM: 602267 MGI: 107825 HomoloGene: 74384 GeneCards: ADAM8 Gene
EC number	3.4.24.-
هستی‌شناسی ژن Molecular function • metalloendopeptidase activity • calcium ion binding • protein binding • metallopeptidase activity • zinc ion binding • protein self-association • cell adhesion molecule binding Cellular component • podosome • cytoplasm • plasma membrane • integral to plasma membrane • cell surface • phagolysosome • dense core granule membrane • specific granule • tertiary granule • alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex • alpha9-beta1 integrin-ADAM8 complex Biological process • cell morphogenesis • angiogenesis • leukocyte migration involved in inflammatory response • positive regulation of acute inflammatory response • proteolysis • inflammatory response • positive regulation of protein processing • regulation of cell-cell adhesion • positive regulation of T cell differentiation in thymus • activation of MAPK activity involved in innate immune response • negative regulation of neuron apoptotic process • positive regulation of bone resorption • positive regulation of cell adhesion • lymphocyte chemotaxis • positive regulation of protein secretion • positive regulation of membrane protein ectodomain proteolysis • positive regulation of NF-kappaB transcription factor activity • positive regulation of protein kinase B signaling cascade • positive regulation of thymocyte apoptotic process • cellular response to hypoxia • positive regulation of tumor necrosis factor (ligand) superfamily member 11 production • positive regulation of neutrophil extravasation • positive regulation of fibronectin-dependent thymocyte migration • positive regulation of eosinophil migration Sources: Amigo / QuickGO
الگوی بیان RNA
دادهای بیان مرجع بیشتر
اورتولوگ
گونه‌ها	انسان	موش
آنتره	101	11501
آنسامبل	ENSG00000151651	ENSMUSG00000025473
UniProt	P78325	Q05910
RefSeq (mRNA)	NM_001109.4	NM_007403.2
RefSeq (protein)	NP_001100.3	NP_031429.1
موقعیت (UCSC)	Chr 10: 135.08 – 135.09 Mb	Chr 7: 139.98 – 139.99 Mb
جستجوی پاب‌مد	[۱]	[۲]